Sensing the difference: The influence of anisotropic cues on cell behavior

José Ballester-Beltrán, Manus J.P. Biggs, Matthew J. Dalby, Manuel Salmerón-Sánchez, Aldo Leal-Egaña

研究成果: ジャーナルへの寄稿総説査読

27 被引用数 (Scopus)


From tissue morphogenesis to homeostasis, cells continuously experience and respond to physical, chemical, and biological cues commonly presented in gradients. In this article, we focus our discussion on the importance of nano/micro topographic cues on cell activity, and the role of anisotropic milieus play on cell behavior, mostly adhesion and migration. We present the need to study physiological gradients in vitro. To do this, we review different cell migration mechanisms and how adherent cells react to the presence of complex tissue-like environments and cell-surface stimulation in 2D and 3D (e.g., ventral/dorsal anisotropy).

ジャーナルFrontiers in Materials
出版ステータス出版済み - 5月 8 2015

!!!All Science Journal Classification (ASJC) codes

  • 材料科学(その他)


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