Sequence and expression of transcripts of the human T-cell receptor β- chain genes

Yasunobu Yoshikai, Demetri Anatoniou, Stephen P. Clark, Yusuke Yanagi, Robert Sangster, Peter Van Den Elsen, Cox Terhorst, Tak W. Mak

    研究成果: Contribution to journalArticle査読

    289 被引用数 (Scopus)

    抄録

    T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.

    本文言語英語
    ページ(範囲)521-524
    ページ数4
    ジャーナルNature
    312
    5994
    DOI
    出版ステータス出版済み - 1984

    All Science Journal Classification (ASJC) codes

    • 一般

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