Sequence and expression of transcripts of the human T-cell receptor β- chain genes

Yasunobu Yoshikai; Demetri Anatoniou; Stephen P. Clark; Yusuke Yanagi; Robert Sangster; Peter Van Den Elsen; Cox Terhorst; Tak W. Mak

doi:10.1038/312521a0

Sequence and expression of transcripts of the human T-cell receptor β- chain genes

Yasunobu Yoshikai, Demetri Anatoniou, Stephen P. Clark, Yusuke Yanagi, Robert Sangster, Peter Van Den Elsen, Cox Terhorst, Tak W. Mak

研究成果: Contribution to journal › Article › 査読

289 被引用数 (Scopus)

抄録

T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.

本文言語	英語
ページ（範囲）	521-524
ページ数	4
ジャーナル	Nature
巻	312
号	5994
DOI	https://doi.org/10.1038/312521a0
出版ステータス	出版済み - 1984

All Science Journal Classification (ASJC) codes

一般

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10.1038/312521a0

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abstract = "T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.",

author = "Yasunobu Yoshikai and Demetri Anatoniou and Clark, {Stephen P.} and Yusuke Yanagi and Robert Sangster and {Van Den Elsen}, Peter and Cox Terhorst and Mak, {Tak W.}",

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doi = "10.1038/312521a0",

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AU - Yoshikai, Yasunobu

AU - Anatoniou, Demetri

AU - Clark, Stephen P.

AU - Yanagi, Yusuke

AU - Sangster, Robert

AU - Van Den Elsen, Peter

AU - Terhorst, Cox

AU - Mak, Tak W.

PY - 1984

Y1 - 1984

N2 - T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.

AB - T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.

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JO - Nature

JF - Nature

SN - 0028-0836

IS - 5994

ER -

Sequence and expression of transcripts of the human T-cell receptor β- chain genes

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