Serum appearance of anti-p53 antibody in triple negative breast cancer

Tadahiro Nozoe, Emiko Mori, Mayuko Kono, Tomohiro Iguchi, Takashi Maeda, Akito Matsukuma, Takahiro Ezaki

研究成果: Contribution to journalArticle査読

7 被引用数 (Scopus)

抄録

Background: Significance of serum appearance of anti-p53 antibody in breast cancer has not been discussed fully. Methods: The relationship between serum appearance of anti-p53 antibody and the clinicopathological features was investigated on the basis of the data of 42 women with breast cancer who had been treated with surgical resection. Results: The proportion of tumors with histological grade 3 was significantly higher among tumors with serum appearance of anti-p53 antibody (P = 0.020). The proportion of triple negative tumors was also significantly higher among tumors with serum appearance of anti-p53 antibody (P = 0.003). Conclusions: Preoperative appearance of anti-p53 antibody in sera can be correlated with the incidence of triple negative breast cancer and could therefore help identify tumors with aggressive potential.

本文言語英語
ページ(範囲)11-15
ページ数5
ジャーナルBreast Cancer
19
1
DOI
出版ステータス出版済み - 1 2012

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 放射線学、核医学およびイメージング
  • 薬理学(医学)

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