Shape of α-crystallin analyzed by small-angle neutron scattering

Masaaki Sugiyama, Noriko Fujii, Yukio Morimoto, Toshiya Otomo, Shinichi Takata, Masakatsu Misawa, Masahiko Annaka, Keiji Itoh, Kazuhiro Mori, Takashi Sato, Sakie Kurabayashi, Toshiharu Fukunaga

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

The size and shape of aggregates of human recombinant αA-crystallin and αB-crystallin are investigated with small-angle neutron scattering and dynamic light scattering. At a bioactive temperature (310 K), both polypeptides form aggregates with almost the same size and shape. The αB-crystallin maintains an almost identical size and shape at 310 and 288 K, whereas the aggregate of αA-crystallin shows deformation at 288 K. This result suggests that at the lower temperature there is a difference in structural stability between the two aggregates of the polypeptides.

元の言語英語
ページ(範囲)s200-s204
ジャーナルJournal of Applied Crystallography
40
発行部数SUPPL. 1
DOI
出版物ステータス出版済み - 4 1 2007

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Small Angle Scattering
Crystallins
Neutrons
Neutron scattering
neutron scattering
polypeptides
Peptides
Temperature
structural stability
Dynamic light scattering
activity (biology)
light scattering
temperature

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

これを引用

Sugiyama, M., Fujii, N., Morimoto, Y., Otomo, T., Takata, S., Misawa, M., ... Fukunaga, T. (2007). Shape of α-crystallin analyzed by small-angle neutron scattering. Journal of Applied Crystallography, 40(SUPPL. 1), s200-s204. https://doi.org/10.1107/S0021889807006838

Shape of α-crystallin analyzed by small-angle neutron scattering. / Sugiyama, Masaaki; Fujii, Noriko; Morimoto, Yukio; Otomo, Toshiya; Takata, Shinichi; Misawa, Masakatsu; Annaka, Masahiko; Itoh, Keiji; Mori, Kazuhiro; Sato, Takashi; Kurabayashi, Sakie; Fukunaga, Toshiharu.

:: Journal of Applied Crystallography, 巻 40, 番号 SUPPL. 1, 01.04.2007, p. s200-s204.

研究成果: ジャーナルへの寄稿記事

Sugiyama, M, Fujii, N, Morimoto, Y, Otomo, T, Takata, S, Misawa, M, Annaka, M, Itoh, K, Mori, K, Sato, T, Kurabayashi, S & Fukunaga, T 2007, 'Shape of α-crystallin analyzed by small-angle neutron scattering', Journal of Applied Crystallography, 巻. 40, 番号 SUPPL. 1, pp. s200-s204. https://doi.org/10.1107/S0021889807006838
Sugiyama M, Fujii N, Morimoto Y, Otomo T, Takata S, Misawa M その他. Shape of α-crystallin analyzed by small-angle neutron scattering. Journal of Applied Crystallography. 2007 4 1;40(SUPPL. 1):s200-s204. https://doi.org/10.1107/S0021889807006838
Sugiyama, Masaaki ; Fujii, Noriko ; Morimoto, Yukio ; Otomo, Toshiya ; Takata, Shinichi ; Misawa, Masakatsu ; Annaka, Masahiko ; Itoh, Keiji ; Mori, Kazuhiro ; Sato, Takashi ; Kurabayashi, Sakie ; Fukunaga, Toshiharu. / Shape of α-crystallin analyzed by small-angle neutron scattering. :: Journal of Applied Crystallography. 2007 ; 巻 40, 番号 SUPPL. 1. pp. s200-s204.
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