Signal pathway analysis with differentiation markers in osteoblasts stimulated by synthetic analogue to bone mineral

Ryuhei Nishikawa, Takahisa Anada, Osamu Suzuki

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

抄録

OCTACALCIUM PHOSPHATE (Ca8H2(PO4) 6·5H2O; OCP) is considered as a precursor of biological apatite crystals in bone and tooth in vertebrates. Recent studies have suggested that osteoblastic cell differentiation is enhanced in contact with OCP which is converted into HA and is significantly facilitated in an OCP dose-dependent manner. MAPK signaling is known to be activated in the early stage of the differentiation from bone marrow-derived mesenchymal stem cells into osteoblasts. However, the MAPK signaling is unclear in relation to the stimulatory capacity of OCP in the osteoblastic differentiation. In this study, we investigated the MAPK signaling during the differentiation of bone marrow-derived stromal cell line leading to the late differentiation stage using gene expression analysis.

本文言語英語
ホスト出版物のタイトル2012 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2012
ページ164-168
ページ数5
DOI
出版ステータス出版済み - 12月 1 2012
外部発表はい
イベント23rd Annual Symposium on Micro-Nano Mechatronics and Human Science, MHS 2012 - Nagoya, 日本
継続期間: 11月 4 201211月 7 2012

出版物シリーズ

名前2012 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2012

その他

その他23rd Annual Symposium on Micro-Nano Mechatronics and Human Science, MHS 2012
国/地域日本
CityNagoya
Period11/4/1211/7/12

!!!All Science Journal Classification (ASJC) codes

  • 電子工学および電気工学
  • 機械工学

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