Simultaneous determination of triazolam and its metabolites in human blood and urine by GC/MS

K. Kudo, N. Ikeda, Y. Hino

研究成果: Contribution to journalArticle査読

抄録

A sensitive and selective method has been developed for simultaneous determination of triazolam and its major metabolites, α-hydroxytriazolam and 4-hydroxytriazolam in human whole blood and urine. The drugs were effectively extracted using a 3-step solvent extraction procedure followed by tert-butyldimethylsilyl derivatization, and subjected to GC/MS in the negative ion chemical ionization mode.

本文言語英語
ページ(範囲)137-143
ページ数7
ジャーナルZ Zagadnien Nauk Sadowych
43
出版ステータス出版済み - 2000

All Science Journal Classification (ASJC) codes

  • 病理学および法医学

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