Simultaneous separation, metering and dilution of plasma from human whole blood using a microchip with an interchannel microstructure

Tomoya Tachi, Noritada Kaji, Yukihiro Okamoto, Manabu Tokeshi, Yoshinobu Baba

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

1 被引用数 (Scopus)

抄録

In this research, we designed and operated a microchip with an interchannel microstructure for separation of plasma from human whole blood and for metering and diluting the plasma. The plasma separation was based on both cross-flow filtration and sedimentation of red blood cells in the microchannels. Metering and diluting the plasma was based on volume control of liquid in the microchannels by syringe pumps. Simultaneous operations to separate, meter and dilute plasma obtained from whole blood were done in microchannels using this microchip, and plasma precisely diluted by a factor of 6 was generated without hemolysis in the microchannels in about 3 minutes. This microchip is easily connected with other microchannels and microfluidic devices for quantitative analyses.

本文言語英語
ホスト出版物のタイトルProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ427-429
ページ数3
ISBN(印刷版)9780979806421
出版ステータス出版済み - 2009
外部発表はい
イベント13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, 韓国
継続期間: 11月 1 200911月 5 2009

出版物シリーズ

名前Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

その他

その他13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
国/地域韓国
CityJeju
Period11/1/0911/5/09

!!!All Science Journal Classification (ASJC) codes

  • 化学工学(その他)
  • バイオエンジニアリング

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