TY - JOUR
T1 - Site-directed alkylation to cytidine within duplex by the oligonucleotides containing functional nucleobases
AU - Nagatsugi, Fumi
AU - Kawasaki, Takeshi
AU - Tokuda, Natsuko
AU - Maeda, Minoru
AU - Sasaki, Shigeki
PY - 2001
Y1 - 2001
N2 - We have previously described that oligonucleotides (ODN) containing phenylsulfoxide derivative of 2-amino-6-vinylpurine nucleoside analog (1) are activated within duplex to form cross-link toward cytidine selectively at the target site. In this paper, we wish to report the search for more stable precursor susceptible for activation within duplex.
AB - We have previously described that oligonucleotides (ODN) containing phenylsulfoxide derivative of 2-amino-6-vinylpurine nucleoside analog (1) are activated within duplex to form cross-link toward cytidine selectively at the target site. In this paper, we wish to report the search for more stable precursor susceptible for activation within duplex.
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U2 - 10.1081/NCN-100002458
DO - 10.1081/NCN-100002458
M3 - Article
C2 - 11563144
AN - SCOPUS:0034852293
SN - 1525-7770
VL - 20
SP - 915
EP - 919
JO - Nucleosides, Nucleotides and Nucleic Acids
JF - Nucleosides, Nucleotides and Nucleic Acids
IS - 4-7
ER -