Solitary fibrous tumor of the thyroid gland

Yusuke Mizuuchi, Hidetaka Yamamoto, Katsuya Nakamura, Kengo Shirahane, Masae Souzaki, Masao Tanaka, Yoshinao Oda

研究成果: Contribution to journalArticle査読

8 被引用数 (Scopus)


Solitary fibrous tumor is a spindle cell neoplasm rarely arising in the thyroid gland. We present a 78-year-old man with the diagnosis of solitary fibrous tumor of the thyroid gland resected by subtotal thyroidectomy. Fine needle aspiration cytology via ultrasound guidance demonstrated a hypocellular aspirate that revealed follicular epithelial cells with mild nuclear atypia and scattered spindle cells with bland nuclei. Histologically, the patternless proliferation of spindle cells was seen among collagenous bundles, accompanied by hemangiopericytomatous vessels, and variously dilated follicles with mild atypical cells having slightly enlarged nuclei, indicating adenomatous goiter. The neoplastic spindle cells showed diffuse immunoreactivity to CD34, bcl-2, CD99 and vimentin, but were negative for cytokeratins, calcitonin, TTF-1 and CD5. Although solitary fibrous tumor arising in thyroid gland is rare, this tumor should be included in the differential diagnosis of thyroid spindle cell tumors and also that of adenomatous.

ジャーナルMedical Molecular Morphology
出版ステータス出版済み - 6 2014

All Science Journal Classification (ASJC) codes

  • 病理学および法医学
  • 分子生物学


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