Sonographic analysis of rat submandibular glands in experimentally-induced sialadenitis

M. Shimizu, K. Tokumori, M. Saitoh, K. Miwa, K. Yoshiura, S. Kanda

研究成果: ジャーナルへの寄稿学術誌査読

4 被引用数 (Scopus)


Objectives: To correlate the sonographic features of experimentally-induced obstructive sialadenitis in rat submandibular glands with the his to pathological changes. Materials and methods: Changes in sonograms of ligated and non-ligated rat submandibular glands were compared with the wet weight and histopathology. Sonograms were obtained at 1, 2, 3, 4, 5, 7 and 21 days after duct ligation at 13 and 14 MHz for B-mode and for power Doppler mode respectively. Changes in gland size, echo intensity, distribution of internal echoes and vascularity were evaluated both qualitatively and quantitatively. Results: Changes in size of the ligated glands were very similar to changes in wet weight. The ligated glands showed lower echo intensity than the non-ligated glands. The ligated glands showed higher echo intensity in the central portion at 4 7 days after duct ligation which resulted in heterogeneity of the glands. Vascularity of the ligated glands increased in the acute phase, and then decreased to the level of the non-ligated glands. Conclusions: The three phases in the changes in ligated glands identifiable histopathologically can be differentiated by B-mode sonography. Power Doppler can differentiate the acute phase. Sonography therefore appears useful for the diagnosis of the degree of gland damage.

ジャーナルDentomaxillofacial Radiology
出版ステータス出版済み - 2000

!!!All Science Journal Classification (ASJC) codes

  • 耳鼻咽喉科学
  • 放射線学、核医学およびイメージング
  • 歯科学(全般)


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