Specific recognition of the protein modified with hyaluronan by liver sinusoidal endothelial cells

Shinichi Mochizuki, Arihiro Kano, Asako Yamayoshi, Atsushi Maruyama

研究成果: Contribution to conferencePaper査読

抄録

It has been reported that LSECs have abilities of high phagocytosis and antigen presentation, and induce immune tolerance to specific antigens. To induce specific immune tolerance, it is thought to be important to deliver antigens to the LSECs precisely. We have studied the targeting to LSECs using HA as ligand, reported the bioconjugates composed of HA. In this report, an antigenic protein, OVA, was modified with hyaluronan to induce the antigen specific immune tolerance through selective delivery of antigen to LSECs.

本文言語英語
ページ5177-5178
ページ数2
出版ステータス出版済み - 12 1 2005
イベント54th SPSJ Symposium on Macromolecules - Yamagata, 日本
継続期間: 9 20 20059 22 2005

その他

その他54th SPSJ Symposium on Macromolecules
国/地域日本
CityYamagata
Period9/20/059/22/05

All Science Journal Classification (ASJC) codes

  • 工学(全般)

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