Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff.

Yasodha Sivasothy, A. Hamid A. Hadi, Khalit Mohamad, Kok Hoong Leong, Halijah Ibrahim, Shaida Fariza Sulaiman, Kheng Leong Ooi, Khalijah Awang

研究成果: Contribution to journalArticle査読

7 被引用数 (Scopus)

抄録

The rhizomes of Zingiber spectabile yielded a new dimeric flavonol glycoside for which the name kaempferol-3-O-(4″-O-acetyl)-α-l- rhamnopyranoside-(I-6,II-8)-kaempferol-3-O-(4″-O-acetyl) -α-l-rhamnopyranoside; spectaflavoside A (1) was proposed, along with kaempferol and its four acetylrhamnosides (2-6), demethoxycurcumin (7) and curcumin (8). The structure of spectaflavoside A was elucidated by spectroscopic methods including, 1D and 2D NMR techniques. This is the first report on the occurrence of a dimeric flavonol glycoside in the Zingiberaceae and the second in nature. Spectaflavoside A was found to be a potent iron chelating agent.

本文言語英語
ページ(範囲)3831-3836
ページ数6
ジャーナルBioorganic and Medicinal Chemistry Letters
22
11
DOI
出版ステータス出版済み - 6 1 2012
外部発表はい

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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