Stem cells in dentistry - Part I: Stem cell sources

Hiroshi Egusa, Wataru Sonoyama, Masahiro Nishimura, Atsuta Ikiru, Kentaro Akiyama

研究成果: ジャーナルへの寄稿評論記事

145 引用 (Scopus)

抄録

Stem cells can self-renew and produce different cell types, thus providing new strategies to regenerate missing tissues and treat diseases. In the field of dentistry, adult mesenchymal stem/stromal cells (MSCs) have been identified in several oral and maxillofacial tissues, which suggests that the oral tissues are a rich source of stem cells, and oral stem and mucosal cells are expected to provide an ideal source for genetically reprogrammed cells such as induced pluripotent stem (iPS) cells. Furthermore, oral tissues are expected to be not only a source but also a therapeutic target for stem cells, as stem cell and tissue engineering therapies in dentistry continue to attract increasing clinical interest. Part I of this review outlines various types of intra- and extra-oral tissue-derived stem cells with regard to clinical availability and applications in dentistry. Additionally, appropriate sources of stem cells for regenerative dentistry are discussed with regard to differentiation capacity, accessibility and possible immunomodulatory properties.

元の言語英語
ページ(範囲)151-165
ページ数15
ジャーナルJournal of Prosthodontic Research
56
発行部数3
DOI
出版物ステータス出版済み - 7 1 2012

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Dentistry
Stem Cells
Mesenchymal Stromal Cells
Cell Engineering
Induced Pluripotent Stem Cells
Adult Stem Cells
Tissue Engineering
Cell- and Tissue-Based Therapy

All Science Journal Classification (ASJC) codes

  • Oral Surgery
  • Dentistry (miscellaneous)

これを引用

Stem cells in dentistry - Part I : Stem cell sources. / Egusa, Hiroshi; Sonoyama, Wataru; Nishimura, Masahiro; Ikiru, Atsuta; Akiyama, Kentaro.

:: Journal of Prosthodontic Research, 巻 56, 番号 3, 01.07.2012, p. 151-165.

研究成果: ジャーナルへの寄稿評論記事

Egusa, H, Sonoyama, W, Nishimura, M, Ikiru, A & Akiyama, K 2012, 'Stem cells in dentistry - Part I: Stem cell sources', Journal of Prosthodontic Research, 巻. 56, 番号 3, pp. 151-165. https://doi.org/10.1016/j.jpor.2012.06.001
Egusa, Hiroshi ; Sonoyama, Wataru ; Nishimura, Masahiro ; Ikiru, Atsuta ; Akiyama, Kentaro. / Stem cells in dentistry - Part I : Stem cell sources. :: Journal of Prosthodontic Research. 2012 ; 巻 56, 番号 3. pp. 151-165.
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