Steroidal saponins from Smilax medica and their antifungal activity

Marc Sautour, Tomofumi Miyamoto, Marie Aleth Lacaille-Dubois

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

抜粋

Three new steroidal saponins (1-3) were isolated from the roots of Smilax medica, together with the known disporoside A (4). The structures of the new compounds were elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR, FABMS, and HRESIMS). Compounds 1,2, and 4 demonstrated weak antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata, and C. tropicalis, with MIC values between 12.5 and 50 μg/mL.

元の言語英語
ページ(範囲)1489-1493
ページ数5
ジャーナルJournal of Natural Products
68
発行部数10
DOI
出版物ステータス出版済み - 10 1 2005

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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