Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection

Sayaka Okuzono, Masataka Ishimura, Shunsuke Kanno, Motoshi Sonoda, Noriyuki Kaku, Yoshitomo Motomura, Hisanori Nishio, Utako Oba, Masuo Hanada, Jun ichi Fukushi, Michiyo Urata, Dongchon Kang, Hidetoshi Takada, Shouichi Ohga

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

抜粋

Background: Streptococcus pyogenes is an uncommon pathogen of purpura fulminans, and the pathogenesis of S. pyogenes-purpura fulminans remains unclear because of paucity of cases. We reported a pediatric case of S. pyogenes-purpura fulminans with literature review of the disease. Case presentation: A 3-year-old boy showed limping, lethargy and acral gangrene within 24 h. A diagnosis of S. pyogenes-purpura fulminans was made for bacterial isolation from throat and peripheral blood. Intensive therapy led to a survival with amputation of the left distal metatarsal bone, and normal development. The isolated M12 carried no mutation of csrS/R or rgg. Thrombophilia or immunodeficiency was excluded. Discussion: Twelve-reported cases (9 pediatric and 3 elderly) of S. pyogenes-purpura fulminans started with shock and coagulopathy. Five patients age < 8 years had no underlying disease and survived. One youngest and two immunocompromised patients died. Conclusion:Streptococcus pyogenes-acute infectious purpura fulminans is a distinctive rare form of aggressive GAS infections.

元の言語英語
記事番号31
ジャーナルAnnals of Clinical Microbiology and Antimicrobials
17
発行部数1
DOI
出版物ステータス出版済み - 7 9 2018

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

フィンガープリント Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用