Stroke in a child safely treated with intravenous tissue plasminogen activator and edaravone, a free radical scavenger

Haruhisa Baba, Hiroshi Sugimori, Etsuro Nanishi, Hazumu Nagata, Sooyoung Lee, Takahiro Kuwashiro, Makoto Hashizume

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

An 11-year-old female felt discomfort in her head, and left hemispheric syndrome occurred shortly thereafter. At presentation, her National Institutes of Health stroke scale (NIHSS) score was 13, and a magnetic resonance imaging scan revealed acute brain infarction in the left thalamus. She was immediately treated with the intravenous administration of tissue plasminogen activator (IV t-PA) followed by edaravone, a free radical scavenger. Two hours after IV t-PA, her symptoms dramatically resolved and her NIHSS score decreased to 5. No adverse events were observed. She was the youngest patient treated with IV t-PA in Japan, and would be the youngest treated in most developed countries. An optimal treatment for stroke in children has not been established, and this case highlights the urgent need to examine the safety and efficacy of IV t-PA and edaravone therapy for ischemic stroke in children.

本文言語英語
ページ(範囲)903.e5-903.e8
ジャーナルJournal of Stroke and Cerebrovascular Diseases
21
8
DOI
出版ステータス出版済み - 11 2012

All Science Journal Classification (ASJC) codes

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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