[Structural basis for measles virus-receptor recognition and its functional implications for viral entry and vaccination].

Katsumi Maenaka, Takao Hashiguchi, Yusuke Yanagi

研究成果: Contribution to journalReview article査読

抄録

Measles is one of the most contagious and devastating viral diseases. However, highly effective live vaccines have been successfully used for more than five decades. Recent structural studies of measles virus hemagglutinin and its complexes with receptors (the signaling lymphocyte activation molecule (SLAM, CD150) and CD46) have provided many insights into measles virus entry mechanism. Furthermore, the sugar shields that cover the large surface areas of the hemagglutinin have implications for effective measles virus vaccination. These studies should help strengthen current global efforts to control and eliminate measles worldwide.

本文言語英語
ページ(範囲)695-703
ページ数9
ジャーナルNihon rinsho. Japanese journal of clinical medicine
70
4
出版ステータス出版済み - 4 2012

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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