Successful chemoradiotherapy for undifferentiated malignant neoplasm arising from the left pulmonary artery

Hozumi Kumagai, Kenta Nio, Yuta Okumura, Masato Komoda, Tsuyoshi Shirakawa, Hitoshi Kusaba, Shioto Yasuda, Keita Odashiro, Shuji Arita, hiroshi ariyama, Yuichi Yamada, Hidetaka Yamamoto, Yoshinao Oda, Katsumasa Nakamura, Koichi Akashi, Eishi Baba

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

Undifferentiated malignant neoplasms, which occur primarily in the pulmonary artery, are extremely rare and associated with poor outcomes as there is no effective therapy. A 67-year-old woman visited our hospital with complaints of dry cough and dyspnea on exertion. A contrast-enhanced chest computed tomography revealed an intravascular tumor obstructing the left pulmonary artery and a pedunculated lesion extending to the main and right pulmonary artery. Multiple metastases in the lung, bones and bilateral adrenal glands were identified by fluorodeoxyglucose-positron emission tomography. A small sample was obtained by catheter aspiration biopsy of the intravascular tumor, and examination revealed undifferentiated small atypical cells. The tumor was diagnosed as an undifferentiated neoplasm arising from the pulmonary artery based on immunohistochemical findings, including the absence of expressions of organ-specific markers. Systemic chemotherapy (paclitaxel and carboplatin) and concurrent radiation were performed as treatment for the primary tumor. Marked shrinkage of the intravascular tumor was achieved, and no serious adverse events were observed during therapy. Chemotherapy was continued for 5 months, but the patient died because of tumor progression 9 months after the initial diagnosis. Chemoradiotherapy has efficacy against undifferentiated neoplasm of the pulmonary artery.

元の言語英語
ページ(範囲)484-490
ページ数7
ジャーナルCase Reports in Oncology
7
発行部数2
DOI
出版物ステータス出版済み - 1 1 2014

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Chemoradiotherapy
Pulmonary Artery
Neoplasms
Drug Therapy
Carboplatin
Needle Biopsy
Adrenal Glands
Paclitaxel
Cough
Positron-Emission Tomography
Dyspnea
Thorax
Therapeutics
Catheters
Tomography
Radiation
Neoplasm Metastasis
Bone and Bones
Lung

All Science Journal Classification (ASJC) codes

  • Oncology

これを引用

Successful chemoradiotherapy for undifferentiated malignant neoplasm arising from the left pulmonary artery. / Kumagai, Hozumi; Nio, Kenta; Okumura, Yuta; Komoda, Masato; Shirakawa, Tsuyoshi; Kusaba, Hitoshi; Yasuda, Shioto; Odashiro, Keita; Arita, Shuji; ariyama, hiroshi; Yamada, Yuichi; Yamamoto, Hidetaka; Oda, Yoshinao; Nakamura, Katsumasa; Akashi, Koichi; Baba, Eishi.

:: Case Reports in Oncology, 巻 7, 番号 2, 01.01.2014, p. 484-490.

研究成果: ジャーナルへの寄稿記事

Kumagai, Hozumi ; Nio, Kenta ; Okumura, Yuta ; Komoda, Masato ; Shirakawa, Tsuyoshi ; Kusaba, Hitoshi ; Yasuda, Shioto ; Odashiro, Keita ; Arita, Shuji ; ariyama, hiroshi ; Yamada, Yuichi ; Yamamoto, Hidetaka ; Oda, Yoshinao ; Nakamura, Katsumasa ; Akashi, Koichi ; Baba, Eishi. / Successful chemoradiotherapy for undifferentiated malignant neoplasm arising from the left pulmonary artery. :: Case Reports in Oncology. 2014 ; 巻 7, 番号 2. pp. 484-490.
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AU - Yamada, Yuichi

AU - Yamamoto, Hidetaka

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AU - Baba, Eishi

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