Successful Endoscopic Treatment of Post-esophagectomy Refractory Reflux Using OverStitch: The First Clinical Case

Hirotsugu Nagase, Makoto Yamasaki, Yoshitomo Yanagimoto, Takashi Kanemura, Shigeyoshi Higashi, Kota Momose, Ryo Kato, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Hiroshi Miyata, Shuji Takiguchi, Masaki Mori, Yuichiro Doki, Kiyokazu Nakajima

研究成果: Contribution to journalArticle

抜粋

Aims: The reflux of duodeno-gastric contents into the remnant esophagus (gastric tube-esophageal reflux: GTER) is a significant issues in long-term esophageal cancer survivors after radical esophagectomy. We attempted endoscopic valve (funnel) creation for prevention for GTER using OverStitch endoscopic suturing system. Methods: The OverStitch was mounted onto a standard double-channel endoscope. Under general anesthesia, the funnel creation was attempted by placing semi-full thickness sutures on the gastric wall, at 3 cm distal to the primary esophago-gastric anastomosis. The postoperative outcomes were also evaluated. Results: In total, 4 sutures were needed and the operating time was 62 minutes without complication. The endoscopic and swallowing studies, as well as pH profile, were all improved postoperatively. The patient’s quality of life was dramatically improved with complete disappearance of night-time reflux in spine position. Conclusions: Endoscopic antireflux funnel creation was feasible and safe. This procedure may become a useful treatment for patients with severe GTER after esophagectomy.

元の言語英語
ジャーナルClinical Medicine Insights: Gastroenterology
11
DOI
出版物ステータス出版済み - 7 2 2018
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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    Nagase, H., Yamasaki, M., Yanagimoto, Y., Kanemura, T., Higashi, S., Momose, K., Kato, R., Miyazaki, Y., Makino, T., Takahashi, T., Kurokawa, Y., Miyata, H., Takiguchi, S., Mori, M., Doki, Y., & Nakajima, K. (2018). Successful Endoscopic Treatment of Post-esophagectomy Refractory Reflux Using OverStitch: The First Clinical Case. Clinical Medicine Insights: Gastroenterology, 11. https://doi.org/10.1177/1179552218784946