Successful R0 resection of hilar cholangiocarcinoma by extrahepatic bile duct resection due to accompanying liver dysfunction after neoadjuvant gemcitabine/cisplatin/S-1 combination chemotherapy-a case report

Masaya Higashiguchi, Daisaku Yamada, Hirofumi Akita, Hidetoshi Eguchi, Yoshifumi Iwagami, Tadafumi Asaoka, Takehiro Noda, Kunihito Gotoh, Shogo Kobayashi, Daisuke Sakai, Etsuro Hatano, Tatsuya Loka, Yuichiro Doki, Masaki Mori

研究成果: Contribution to journalReview article

抜粋

A 79-year-old man was referred to our hospital for treatment of hilar cholangiocarcinoma with pathological evidence. FDG-PET/CT and EUS-FNA revealed regional lymph node metastasis and no distant metastasis before the treatment. He received 6 courses of neoadjuvant gemcitabine/cisplatin/S-1 combination chemotherapy, and the imaging studies revealed partial response. However, due to impairment of the liver after chemotherapy, it was difficult to perform subsequent major hepatectomy, and we decided to continue the chemotherapy. The impairment of the liver did not recover following 11 courses of chemotherapy; on the other hand, FDG uptake was diminished on FDG-PET, and cancer cells were not detected by repeated cytology and biopsy. Extrahepatic bile duct resection with dissection of regional lymph nodes was performed, and histopathological examination of the resected specimen suggested RO resection.

元の言語英語
ページ(範囲)342-344
ページ数3
ジャーナルJapanese Journal of Cancer and Chemotherapy
46
発行部数2
出版物ステータス出版済み - 2019

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

フィンガープリント Successful R0 resection of hilar cholangiocarcinoma by extrahepatic bile duct resection due to accompanying liver dysfunction after neoadjuvant gemcitabine/cisplatin/S-1 combination chemotherapy-a case report' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Higashiguchi, M., Yamada, D., Akita, H., Eguchi, H., Iwagami, Y., Asaoka, T., Noda, T., Gotoh, K., Kobayashi, S., Sakai, D., Hatano, E., Loka, T., Doki, Y., & Mori, M. (2019). Successful R0 resection of hilar cholangiocarcinoma by extrahepatic bile duct resection due to accompanying liver dysfunction after neoadjuvant gemcitabine/cisplatin/S-1 combination chemotherapy-a case report. Japanese Journal of Cancer and Chemotherapy, 46(2), 342-344.