Successful treatment of lupus cerebrovascular disease with mycophenolate mofetil

Kazuhiko Higashioka, Kenji Yoshida, Kensuke Oryoji, Kazuo Kamada, Shinichi Mizuki, Hiroshi Tsukamoto, Eisuke Yokota, Koichi Akashi

研究成果: ジャーナルへの寄稿学術誌査読

4 被引用数 (Scopus)

抄録

We report a case of neuropsychiatric systemic lupus erythematosus successfully treated with mycophenolate mofetil (MMF). The patient was a 40-year-old female who maintained with 7 mg of prednisolone plus 100 mg of azathioprine (AZ) per day. According to transient ischemic attack that occurred repeatedly and an elevated level of interleukin-6 (IL-6) in spinal fluid, she was diagnosed as having neuropsychiatric systemic lupus erythematosus (NPSLE). Initial increase in doses of prednisolone and AZ to 20 mg and 150 mg per day, respectively, was ineffective. After switching from AZ to MMF, her symptoms of NPSLE completely resolved with marked improvement of the IL-6 level in her spinal fluid, suggesting that MMF was effective.

本文言語英語
ページ(範囲)2255-2259
ページ数5
ジャーナルInternal Medicine
54
17
DOI
出版ステータス出版済み - 9月 1 2015

!!!All Science Journal Classification (ASJC) codes

  • 内科学

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