Successful treatment of progressive NK cell lymphoma with allogeneic peripheral stem cell transplantation followed by early cyclosporine tapering and donor leukocyte infusions

Masanori Makita, Yoshinobu Maeda, Katsuto Takenaka, Katsuji Shinagawa, Kazutaka Sunami, Yasushi Hiramatsu, Nobuharu Fujii, Fumihiko Ishimaru, Kazuma Ikeda, Kenji Niiya, Tadashi Yoshino, Mine Harada

研究成果: ジャーナルへの寄稿学術誌査読

20 被引用数 (Scopus)

抄録

We describe a patient with progressive natural killer (NK) cell lymphoma who was treated successfully with allogeneic peripheral blood stem cell transplantation (allo-PBSCT) followed by early cyclosporine (CsA) tapering and donor leukocyte infusion (DLI). Because the disease showed early resistance to conventional chemoradiotherapy, we performed high-dose chemotherapy followed by allo-PBSCT. After achieving hematologic engraftment, the patient underwent early tapering of CsA and DLI in an attempt to induce a graft-versus-lymphoma effect. Although the disease was in a progressive state at the time of transplantation, complete remission was obtained after allo-PBSCT. As of this report, the patient has been well for more than 2 years.

本文言語英語
ページ(範囲)94-97
ページ数4
ジャーナルInternational journal of hematology
76
1
DOI
出版ステータス出版済み - 7月 2002

!!!All Science Journal Classification (ASJC) codes

  • 血液学

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