Successful treatment of rapidly progressive interstitial pneumonia with autologous peripheral blood stem cell transplantation in a patient with dermatomyositis

Kensuke Oryoji, Daisuke Himeji, Kouji Nagafuji, Takahiko Horiuchi, Hiroshi Tsukamoto, Hisashi Gondo, Mine Harada

研究成果: Contribution to journalArticle査読

22 被引用数 (Scopus)

抄録

Aggressive autoimmune diseases are often treated by intensive immunosuppressive treatment such as high-dose methylprednisolone and intravenous cyclophosphamide. Autologous hematopoietic stem cell transplantation can facilitate high-dose immunosuppressive therapy (HDIT), which is myeloablative. We describe a 54-year-old female patient with rapidly progressive and refractory interstitial pneumonia due to dermatomyositis, which was successfully treated with high-dose cyclophosphamide and autologous blood stem cell transplantation. Following transplantation, dyspnea disappeared, and arterial blood gas analysis and respiratory function test showed marked improvement. This improvement was confirmed by diminished interstitial shadows on chest X-ray and computed tomography scans. Eighteen months after transplantation, the patient is doing well without symptoms and signs of interstitial pneumonia.

本文言語英語
ページ(範囲)637-640
ページ数4
ジャーナルClinical Rheumatology
24
6
DOI
出版ステータス出版済み - 12 2005

All Science Journal Classification (ASJC) codes

  • Rheumatology

フィンガープリント 「Successful treatment of rapidly progressive interstitial pneumonia with autologous peripheral blood stem cell transplantation in a patient with dermatomyositis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル