Successfully treated abdominal pregnancy causing hemoperitoneum using combined surgical and systemic methotrexate therapy: A case report and review of cases treated at kyushu university hospital

Nobuko Yasutake, Ryosuke Tsunematsu, Hiroko Oishi, Hideaki Yahata, Soko Uchida, Hiroaki Kobayashi, Kiyoko Kato

研究成果: ジャーナルへの寄稿評論記事

5 引用 (Scopus)

抄録

Abdominal pregnancy is a rare condition that accounts for only 1% of all ectopic pregnancies but results in high maternal morbidity and mortality. We present a case of abdominal pregnancy with massive peritoneal bleeding successfully treated using systemic methotrexate (MTX). A 34-year-old woman with amenorrhea for 8 weeks and a positive pregnancy test was referred for evaluation of ectopic pregnancy. Transvaginal ultrasonographic scan showed a gestational sac measuring 25 mm in diameter containing a viable embryo in the cul-de-sac and a considerable amount of free fluid in the patient's lower abdomen and pelvis. Laboratory parameters showed that her hemoglobin concentration was 5.8 g/dl and serum human chorionic gonadotropin concentration was 13,195 mIU/ml. Emergency surgery revealed an abdominal pregnancy in the cul-de-sac and a massive intra-abdominal hemorrhage. After a hemostasis procedure, the patient was successfully treated using systemic MTX. We also present the review of abdominal pregnancy cases treated using systemic MTX at our institution over 10 years. Systemic MTX treatment for abdominal pregnancy is safe and effective and makes it possible to avoid the risk of excessive bleeding by surgical resection of the implantation site.

元の言語英語
ページ(範囲)188-192
ページ数5
ジャーナルGynecologic and Obstetric Investigation
76
発行部数3
DOI
出版物ステータス出版済み - 10 1 2013

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Abdominal Pregnancy
Hemoperitoneum
Methotrexate
Ectopic Pregnancy
Hemorrhage
Gestational Sac
Pregnancy Tests
Therapeutics
Maternal Mortality
Amenorrhea
Chorionic Gonadotropin
Hemostasis
Pelvis
Abdomen
Hemoglobins
Emergencies
Embryonic Structures
Morbidity
Serum

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynaecology

これを引用

Successfully treated abdominal pregnancy causing hemoperitoneum using combined surgical and systemic methotrexate therapy : A case report and review of cases treated at kyushu university hospital. / Yasutake, Nobuko; Tsunematsu, Ryosuke; Oishi, Hiroko; Yahata, Hideaki; Uchida, Soko; Kobayashi, Hiroaki; Kato, Kiyoko.

:: Gynecologic and Obstetric Investigation, 巻 76, 番号 3, 01.10.2013, p. 188-192.

研究成果: ジャーナルへの寄稿評論記事

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abstract = "Abdominal pregnancy is a rare condition that accounts for only 1{\%} of all ectopic pregnancies but results in high maternal morbidity and mortality. We present a case of abdominal pregnancy with massive peritoneal bleeding successfully treated using systemic methotrexate (MTX). A 34-year-old woman with amenorrhea for 8 weeks and a positive pregnancy test was referred for evaluation of ectopic pregnancy. Transvaginal ultrasonographic scan showed a gestational sac measuring 25 mm in diameter containing a viable embryo in the cul-de-sac and a considerable amount of free fluid in the patient's lower abdomen and pelvis. Laboratory parameters showed that her hemoglobin concentration was 5.8 g/dl and serum human chorionic gonadotropin concentration was 13,195 mIU/ml. Emergency surgery revealed an abdominal pregnancy in the cul-de-sac and a massive intra-abdominal hemorrhage. After a hemostasis procedure, the patient was successfully treated using systemic MTX. We also present the review of abdominal pregnancy cases treated using systemic MTX at our institution over 10 years. Systemic MTX treatment for abdominal pregnancy is safe and effective and makes it possible to avoid the risk of excessive bleeding by surgical resection of the implantation site.",
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