Sucking genes into pores: Insight into driven translocation

Takahiro Sakaue

研究成果: Contribution to journalArticle査読

109 被引用数 (Scopus)

抄録

Flexible polymers such as long DNA, RNA molecules, and proteins, can pass through a narrow pore whose size is comparable to their molecular thickness. We highlight the richness and complexity involved in the dynamics of this unique mode of molecular transport, called translocation, actively driven by external forces. In particular, the process takes place in the condition far from equilibrium accompanying of large conformational distortion in line with the propagation of the tensile force along the chain backbone. A general framework is proposed, which captures such essential features, whereby can account for reported various experimental data from a unified viewpoint.

本文言語英語
論文番号041808
ジャーナルPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
81
4
DOI
出版ステータス出版済み - 4 27 2010

All Science Journal Classification (ASJC) codes

  • 統計物理学および非線形物理学
  • 統計学および確率
  • 凝縮系物理学

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