Sudden unexpected death of a methamphetamine abuser with cardiopulmonary abnormalities: A case report

Naoki Nishida, Noriaki Ikeda, Keiko Kudo, Rie Esaki

研究成果: ジャーナルへの寄稿学術誌査読

24 被引用数 (Scopus)

抄録

A 51-year-old man suddenly collapsed while being arrested. He was an abuser of methamphetamine (MP) with a history of previous convictions. The blood MP concentration at autopsy was below the lethal level. The heart revealed hypertrophy and endocardial thickening of the bilateral ventricles. On microscopic examination, the typical findings of hypertrophic cardiomyopathy were not seen, however endocardial thickening with increasing elastic fibres was seen in all the ventricles and in the atria. In the conduction system, the AV node artery with luminal narrowing was longitudinally compressed by circumferential tissue. Severe interstitial fibrosis and small scar formation of the superior ventricular septum were also seen. In addition, diffuse hypertensive pulmonary arteriopathy was seen in the lung parenchyma. We surmise that the AV node artery had been chronically compressed by the circumferential architecture, due to a chronic increase in intracardiac pressure. We believe that the pathological lesions noted in both the cardiac conduction system and the lung in our case may be a complication of MP abuse, and that an MP abuser with such lesions could easily die suddenly upon experiencing emotional stress.

本文言語英語
ページ(範囲)267-271
ページ数5
ジャーナルMedicine, Science and the Law
43
3
DOI
出版ステータス出版済み - 7月 2003

!!!All Science Journal Classification (ASJC) codes

  • 諸問題の倫理的、法的側面
  • 健康政策
  • 法学

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