抄録
Two chiral salen-Co(II) complexes, (R)-7 and (R)-8 bearing two boronic acid groups were synthesized. The saccharide-binding event was conveniently monitored by a spectral change in UV-vis absorption spectroscopy arising from saccharide-boronic acids complexation. Since the distance between the two boronic acid groups is shorter than other diboronic acid-based receptors, the saccharide selectivity is quite different from other systems: the largest association constant was observed for fructose and the next for talose. In addition, chiral recognition was achieved for certain saccharides: the largest discrimination was 2.1 observed for (R)-7 with D/L-allose. These results indicate that the salen-metal complexes provide an excellent basic skeleton for designing the chiral sugar sensing systems.
本文言語 | 英語 |
---|---|
ページ(範囲) | 9455-9468 |
ページ数 | 14 |
ジャーナル | Tetrahedron |
巻 | 55 |
号 | 31 |
DOI | |
出版ステータス | 出版済み - 7月 30 1999 |
!!!All Science Journal Classification (ASJC) codes
- 生化学
- 創薬
- 有機化学