Suppression of band broadening in monodispersed and polydispersed micropillar array columns in liquid chromatography

T. Iwaba, T. Naito, T. Kubo, K. Otsuka

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

Suppression of band broadening in liquid chromatography is important to improve column efficiency. We investigate a mechanism of band broadening in the monodispersed and polydispersed microstructured-columns. The bed porosity and pillar size distribution were controlled in these columns by using microfabrication techniques. The decrease of the bed porosity increased the A term in the Knox plot. The polydispersed pillar columns decreased the B and C terms. These results suggested that the decrease of stagnation in microchannel caused the suppression of band broadening.

本文言語英語
ホスト出版物のタイトル20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
出版社Chemical and Biological Microsystems Society
ページ1426-1427
ページ数2
ISBN(電子版)9780979806490
出版ステータス出版済み - 2016
外部発表はい
イベント20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, アイルランド
継続期間: 10 9 201610 13 2016

出版物シリーズ

名前20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

その他

その他20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
国/地域アイルランド
CityDublin
Period10/9/1610/13/16

All Science Journal Classification (ASJC) codes

  • 制御およびシステム工学

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