Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

Hiroki Obayashi; Rie Wakabayashi; Noriho Kamiya; Masahiro Goto

doi:10.1039/d2cc05910j

Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

Hiroki Obayashi, Rie Wakabayashi, Noriho Kamiya, Masahiro Goto

分子生命工学

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

1 被引用数 (Scopus)

抄録

This study investigated the localization of artificial peptide supramolecular fibers in liquid-liquid phase separation (LLPS). Hierarchical organization led to the localization of supramolecules in LLPS droplets. Moreover, proteins were recruited into confined droplets by the physical adsorption of proteins on the supramolecules, enabling an enhanced cascade reaction.

本文言語	英語
ページ（範囲）	414-417
ページ数	4
ジャーナル	Chemical Communications
巻	59
号	4
DOI	https://doi.org/10.1039/d2cc05910j
出版ステータス	出版済み - 12月 5 2022

!!!All Science Journal Classification (ASJC) codes

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学 (全般)
表面、皮膜および薄膜
金属および合金
材料化学

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10.1039/d2cc05910j

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title = "Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets",

abstract = "This study investigated the localization of artificial peptide supramolecular fibers in liquid-liquid phase separation (LLPS). Hierarchical organization led to the localization of supramolecules in LLPS droplets. Moreover, proteins were recruited into confined droplets by the physical adsorption of proteins on the supramolecules, enabling an enhanced cascade reaction.",

author = "Hiroki Obayashi and Rie Wakabayashi and Noriho Kamiya and Masahiro Goto",

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T1 - Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

AU - Obayashi, Hiroki

AU - Wakabayashi, Rie

AU - Kamiya, Noriho

AU - Goto, Masahiro

PY - 2022/12/5

Y1 - 2022/12/5

N2 - This study investigated the localization of artificial peptide supramolecular fibers in liquid-liquid phase separation (LLPS). Hierarchical organization led to the localization of supramolecules in LLPS droplets. Moreover, proteins were recruited into confined droplets by the physical adsorption of proteins on the supramolecules, enabling an enhanced cascade reaction.

AB - This study investigated the localization of artificial peptide supramolecular fibers in liquid-liquid phase separation (LLPS). Hierarchical organization led to the localization of supramolecules in LLPS droplets. Moreover, proteins were recruited into confined droplets by the physical adsorption of proteins on the supramolecules, enabling an enhanced cascade reaction.

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U2 - 10.1039/d2cc05910j

DO - 10.1039/d2cc05910j

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VL - 59

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EP - 417

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Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

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!!!All Science Journal Classification (ASJC) codes

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