Surface modification of titanium by hydrothermal treatment in Mg-containing solution and early osteoblast responses

Xingling Shi, Masaharu Nakagawa, Giichiro Kawachi, Lingli Xu, Kunio Ishikawa

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

抄録

Surface modification on titanium was carried out in order to improve its bioactivity. Pure titanium was hydrothermally treated in distilled water and 0.1 M MgCl 2 solutions at 200°C for 24 h. Surface morphology, roughness, wettability and chemical composition were characterized before and after treatment. Bovine serum albumin was used as model to study protein adsorption. MC3T3-E1 cells were cultured and initial cell attachment, morphology, proliferation were evaluated. After hydrothermal treatment, nano-sized precipitations were observed and samples showed superhydrophilicity. Magnesium (Mg) was immobilized into titanium surface by hydrothermal treatment. Protein adsorption was significantly increased on Mgcontaining samples. Cell attachment was improved and cell spreading was enhanced on Mg-containing samples compared with untreated or those treated in distilled water. Increased early cellular attachment on the MgTi surface resulted in subsequent increase of number of proliferated cells. Hydrothermal treatment in MgCl 2 solution was expected to be an effective method to fabricate titanium implant with good bioactivity.

元の言語英語
ページ(範囲)1281-1290
ページ数10
ジャーナルJournal of Materials Science: Materials in Medicine
23
発行部数5
DOI
出版物ステータス出版済み - 5 1 2012

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Osteoblasts
Titanium
Magnesium
Surface treatment
Bioactivity
Adsorption
Wettability
Proteins
Water
Bovine Serum Albumin
Surface morphology
Wetting
Cultured Cells
Cell Count
Surface roughness
Chemical analysis

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

これを引用

Surface modification of titanium by hydrothermal treatment in Mg-containing solution and early osteoblast responses. / Shi, Xingling; Nakagawa, Masaharu; Kawachi, Giichiro; Xu, Lingli; Ishikawa, Kunio.

:: Journal of Materials Science: Materials in Medicine, 巻 23, 番号 5, 01.05.2012, p. 1281-1290.

研究成果: ジャーナルへの寄稿記事

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