Surface plasmon resonance in monitoring of complement activation on biomaterials

Yusuke Arima, Mitsuaki Toda, Hiroo Iwata

研究成果: ジャーナルへの寄稿総説査読

27 被引用数 (Scopus)

抄録

When artificial materials come into contact with blood, various biological responses are induced. For successful development of biomaterials used in biomedical devices that will be exposed to blood, understanding and control of these interactions are essential. Surface plasmon resonance (SPR) spectroscopy is one of the surface-sensitive optical methods to monitor biological interactions. SPR enables real-time and in situ analysis of interfacial events associated with biomaterials research. In this review, we describe an SPR biosensor and its application to monitor complement activation onto biomaterials surface. We also discuss the effect of surface properties of the material on complement activation.

本文言語英語
ページ(範囲)988-999
ページ数12
ジャーナルAdvanced Drug Delivery Reviews
63
12
DOI
出版ステータス出版済み - 9月 16 2011
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 薬科学

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