Surgical strategy according to the anatomical types of congenital portosystemic shunts in children

Toshiharu Matsuura, Yoshiaki Takahashi, Yusuke Yanagi, Koichiro Yoshimaru, Kenichiro Yamamura, Eiji Morihana, Hazumu Nagata, Kiyoshi Uike, Hidetoshi Takada, Tomoaki Taguchi

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抄録

Background Congenital portosystemic shunts (CPSS) with intrahepatic portal vein (IHPV) hypoplasia or absence cause encephalopathy or pulmonary hypertension (PH). Acute shunt closure may result in postoperative portal hypertension. The aim of this study was to propose a surgical strategy according to the anatomical types of CPSS and IHPV. Methods Twenty-three CPSS patients were diagnosed from1990 to 2015. All patients were evaluated by computed tomography, angiography, and PV pressure monitoring under a shunt occlusion test. CPSS were categorized into 5 types according to the anatomical shunt location. Results The median age at diagnosis was 34 months. Three of 23 total patients, who had an extrahepatic portosystemic shunt with a hypoplastic IHPV, died before treatment initiation because of severe PH. Fourteen cases received surgical or interventional treatment at the median age of 5 years. A total of 6 cases received surgical therapy, including liver transplants for 2 absent IHPV cases. The remaining 8 cases received interventional coiling. All shunt ligations were successfully accomplished in 1-stage ligation without any complications. After the treatment, the hypoplastic IHPV gradually enlarged with an efficient portal inflow. Conclusion A precise pretreatment anatomical evaluation of CPSS and IHPV types is mandatory for the selection of surgical treatment. Level of evidence Diagnostic study – level II and treatment study – level III.

元の言語英語
ページ(範囲)2099-2104
ページ数6
ジャーナルJournal of Pediatric Surgery
51
発行部数12
DOI
出版物ステータス出版済み - 12 1 2016

Fingerprint

Surgical Portasystemic Shunt
Portal Vein
Pulmonary Hypertension
Ligation
Therapeutics
Brain Diseases
Portal Hypertension
Transplants
Pressure
Liver

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health

これを引用

Surgical strategy according to the anatomical types of congenital portosystemic shunts in children. / Matsuura, Toshiharu; Takahashi, Yoshiaki; Yanagi, Yusuke; Yoshimaru, Koichiro; Yamamura, Kenichiro; Morihana, Eiji; Nagata, Hazumu; Uike, Kiyoshi; Takada, Hidetoshi; Taguchi, Tomoaki.

:: Journal of Pediatric Surgery, 巻 51, 番号 12, 01.12.2016, p. 2099-2104.

研究成果: ジャーナルへの寄稿記事

Matsuura, Toshiharu ; Takahashi, Yoshiaki ; Yanagi, Yusuke ; Yoshimaru, Koichiro ; Yamamura, Kenichiro ; Morihana, Eiji ; Nagata, Hazumu ; Uike, Kiyoshi ; Takada, Hidetoshi ; Taguchi, Tomoaki. / Surgical strategy according to the anatomical types of congenital portosystemic shunts in children. :: Journal of Pediatric Surgery. 2016 ; 巻 51, 番号 12. pp. 2099-2104.
@article{fd64882af89649edaa1f15b00d453a47,
title = "Surgical strategy according to the anatomical types of congenital portosystemic shunts in children",
abstract = "Background Congenital portosystemic shunts (CPSS) with intrahepatic portal vein (IHPV) hypoplasia or absence cause encephalopathy or pulmonary hypertension (PH). Acute shunt closure may result in postoperative portal hypertension. The aim of this study was to propose a surgical strategy according to the anatomical types of CPSS and IHPV. Methods Twenty-three CPSS patients were diagnosed from1990 to 2015. All patients were evaluated by computed tomography, angiography, and PV pressure monitoring under a shunt occlusion test. CPSS were categorized into 5 types according to the anatomical shunt location. Results The median age at diagnosis was 34 months. Three of 23 total patients, who had an extrahepatic portosystemic shunt with a hypoplastic IHPV, died before treatment initiation because of severe PH. Fourteen cases received surgical or interventional treatment at the median age of 5 years. A total of 6 cases received surgical therapy, including liver transplants for 2 absent IHPV cases. The remaining 8 cases received interventional coiling. All shunt ligations were successfully accomplished in 1-stage ligation without any complications. After the treatment, the hypoplastic IHPV gradually enlarged with an efficient portal inflow. Conclusion A precise pretreatment anatomical evaluation of CPSS and IHPV types is mandatory for the selection of surgical treatment. Level of evidence Diagnostic study – level II and treatment study – level III.",
author = "Toshiharu Matsuura and Yoshiaki Takahashi and Yusuke Yanagi and Koichiro Yoshimaru and Kenichiro Yamamura and Eiji Morihana and Hazumu Nagata and Kiyoshi Uike and Hidetoshi Takada and Tomoaki Taguchi",
year = "2016",
month = "12",
day = "1",
doi = "10.1016/j.jpedsurg.2016.09.046",
language = "English",
volume = "51",
pages = "2099--2104",
journal = "Journal of Pediatric Surgery",
issn = "0022-3468",
publisher = "W.B. Saunders Ltd",
number = "12",

}

TY - JOUR

T1 - Surgical strategy according to the anatomical types of congenital portosystemic shunts in children

AU - Matsuura, Toshiharu

AU - Takahashi, Yoshiaki

AU - Yanagi, Yusuke

AU - Yoshimaru, Koichiro

AU - Yamamura, Kenichiro

AU - Morihana, Eiji

AU - Nagata, Hazumu

AU - Uike, Kiyoshi

AU - Takada, Hidetoshi

AU - Taguchi, Tomoaki

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background Congenital portosystemic shunts (CPSS) with intrahepatic portal vein (IHPV) hypoplasia or absence cause encephalopathy or pulmonary hypertension (PH). Acute shunt closure may result in postoperative portal hypertension. The aim of this study was to propose a surgical strategy according to the anatomical types of CPSS and IHPV. Methods Twenty-three CPSS patients were diagnosed from1990 to 2015. All patients were evaluated by computed tomography, angiography, and PV pressure monitoring under a shunt occlusion test. CPSS were categorized into 5 types according to the anatomical shunt location. Results The median age at diagnosis was 34 months. Three of 23 total patients, who had an extrahepatic portosystemic shunt with a hypoplastic IHPV, died before treatment initiation because of severe PH. Fourteen cases received surgical or interventional treatment at the median age of 5 years. A total of 6 cases received surgical therapy, including liver transplants for 2 absent IHPV cases. The remaining 8 cases received interventional coiling. All shunt ligations were successfully accomplished in 1-stage ligation without any complications. After the treatment, the hypoplastic IHPV gradually enlarged with an efficient portal inflow. Conclusion A precise pretreatment anatomical evaluation of CPSS and IHPV types is mandatory for the selection of surgical treatment. Level of evidence Diagnostic study – level II and treatment study – level III.

AB - Background Congenital portosystemic shunts (CPSS) with intrahepatic portal vein (IHPV) hypoplasia or absence cause encephalopathy or pulmonary hypertension (PH). Acute shunt closure may result in postoperative portal hypertension. The aim of this study was to propose a surgical strategy according to the anatomical types of CPSS and IHPV. Methods Twenty-three CPSS patients were diagnosed from1990 to 2015. All patients were evaluated by computed tomography, angiography, and PV pressure monitoring under a shunt occlusion test. CPSS were categorized into 5 types according to the anatomical shunt location. Results The median age at diagnosis was 34 months. Three of 23 total patients, who had an extrahepatic portosystemic shunt with a hypoplastic IHPV, died before treatment initiation because of severe PH. Fourteen cases received surgical or interventional treatment at the median age of 5 years. A total of 6 cases received surgical therapy, including liver transplants for 2 absent IHPV cases. The remaining 8 cases received interventional coiling. All shunt ligations were successfully accomplished in 1-stage ligation without any complications. After the treatment, the hypoplastic IHPV gradually enlarged with an efficient portal inflow. Conclusion A precise pretreatment anatomical evaluation of CPSS and IHPV types is mandatory for the selection of surgical treatment. Level of evidence Diagnostic study – level II and treatment study – level III.

UR - http://www.scopus.com/inward/record.url?scp=85000350864&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85000350864&partnerID=8YFLogxK

U2 - 10.1016/j.jpedsurg.2016.09.046

DO - 10.1016/j.jpedsurg.2016.09.046

M3 - Article

C2 - 27697318

AN - SCOPUS:85000350864

VL - 51

SP - 2099

EP - 2104

JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

SN - 0022-3468

IS - 12

ER -