Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder: Auditory-evoked response in children with autism spectrum disorder

Yuko Yoshimura, Mitsuru Kikuchi, Hirotoshi Hiraishi, Chiaki Hasegawa, Tetsuya Takahashi, Gerard Bastiaan Remijn, Manabu Oi, Toshio Munesue, Haruhiro Higashida, Yoshio Minabe

研究成果: ジャーナルへの寄稿記事

抄録

The auditory-evoked P1m, recorded by magnetoencephalography, reflects a central auditory processing ability in human children. One recent study revealed that asynchrony of P1m between the right and left hemispheres reflected a central auditory processing disorder (i.e., attention deficit hyperactivity disorder, ADHD) in children. However, to date, the relationship between auditory P1m right-left hemispheric synchronization and the comorbidity of hyperactivity in children with autism spectrum disorder (ASD) is unknown. In this study, based on a previous report of an asynchrony of P1m in children with ADHD, to clarify whether the P1m right-left hemispheric synchronization is related to the symptom of hyperactivity in children with ASD, we investigated the relationship between voice-evoked P1m right-left hemispheric synchronization and hyperactivity in children with ASD. In addition to synchronization, we investigated the right-left hemispheric lateralization. Our findings failed to demonstrate significant differences in these values between ASD children with and without the symptom of hyperactivity, which was evaluated using the Autism Diagnostic Observational Schedule, Generic (ADOS-G) subscale. However, there was a significant correlation between the degrees of hemispheric synchronization and the ability to keep still during 12-minute MEG recording periods. Our results also suggested that asynchrony in the bilateral brain auditory processing system is associated with ADHD-like symptoms in children with ASD.

元の言語英語
ページ(範囲)300-305
ページ数6
ジャーナルNeuroImage: Clinical
12
DOI
出版物ステータス出版済み - 1 1 2016

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Auditory Evoked Potentials
Aptitude
Brain
Attention Deficit Disorder with Hyperactivity
Language Development Disorders
Magnetoencephalography
Autism Spectrum Disorder
Autistic Disorder
Comorbidity
Appointments and Schedules

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience

これを引用

Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder : Auditory-evoked response in children with autism spectrum disorder. / Yoshimura, Yuko; Kikuchi, Mitsuru; Hiraishi, Hirotoshi; Hasegawa, Chiaki; Takahashi, Tetsuya; Remijn, Gerard Bastiaan; Oi, Manabu; Munesue, Toshio; Higashida, Haruhiro; Minabe, Yoshio.

:: NeuroImage: Clinical, 巻 12, 01.01.2016, p. 300-305.

研究成果: ジャーナルへの寄稿記事

Yoshimura, Yuko ; Kikuchi, Mitsuru ; Hiraishi, Hirotoshi ; Hasegawa, Chiaki ; Takahashi, Tetsuya ; Remijn, Gerard Bastiaan ; Oi, Manabu ; Munesue, Toshio ; Higashida, Haruhiro ; Minabe, Yoshio. / Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder : Auditory-evoked response in children with autism spectrum disorder. :: NeuroImage: Clinical. 2016 ; 巻 12. pp. 300-305.
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abstract = "The auditory-evoked P1m, recorded by magnetoencephalography, reflects a central auditory processing ability in human children. One recent study revealed that asynchrony of P1m between the right and left hemispheres reflected a central auditory processing disorder (i.e., attention deficit hyperactivity disorder, ADHD) in children. However, to date, the relationship between auditory P1m right-left hemispheric synchronization and the comorbidity of hyperactivity in children with autism spectrum disorder (ASD) is unknown. In this study, based on a previous report of an asynchrony of P1m in children with ADHD, to clarify whether the P1m right-left hemispheric synchronization is related to the symptom of hyperactivity in children with ASD, we investigated the relationship between voice-evoked P1m right-left hemispheric synchronization and hyperactivity in children with ASD. In addition to synchronization, we investigated the right-left hemispheric lateralization. Our findings failed to demonstrate significant differences in these values between ASD children with and without the symptom of hyperactivity, which was evaluated using the Autism Diagnostic Observational Schedule, Generic (ADOS-G) subscale. However, there was a significant correlation between the degrees of hemispheric synchronization and the ability to keep still during 12-minute MEG recording periods. Our results also suggested that asynchrony in the bilateral brain auditory processing system is associated with ADHD-like symptoms in children with ASD.",
author = "Yuko Yoshimura and Mitsuru Kikuchi and Hirotoshi Hiraishi and Chiaki Hasegawa and Tetsuya Takahashi and Remijn, {Gerard Bastiaan} and Manabu Oi and Toshio Munesue and Haruhiro Higashida and Yoshio Minabe",
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AU - Hiraishi, Hirotoshi

AU - Hasegawa, Chiaki

AU - Takahashi, Tetsuya

AU - Remijn, Gerard Bastiaan

AU - Oi, Manabu

AU - Munesue, Toshio

AU - Higashida, Haruhiro

AU - Minabe, Yoshio

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AB - The auditory-evoked P1m, recorded by magnetoencephalography, reflects a central auditory processing ability in human children. One recent study revealed that asynchrony of P1m between the right and left hemispheres reflected a central auditory processing disorder (i.e., attention deficit hyperactivity disorder, ADHD) in children. However, to date, the relationship between auditory P1m right-left hemispheric synchronization and the comorbidity of hyperactivity in children with autism spectrum disorder (ASD) is unknown. In this study, based on a previous report of an asynchrony of P1m in children with ADHD, to clarify whether the P1m right-left hemispheric synchronization is related to the symptom of hyperactivity in children with ASD, we investigated the relationship between voice-evoked P1m right-left hemispheric synchronization and hyperactivity in children with ASD. In addition to synchronization, we investigated the right-left hemispheric lateralization. Our findings failed to demonstrate significant differences in these values between ASD children with and without the symptom of hyperactivity, which was evaluated using the Autism Diagnostic Observational Schedule, Generic (ADOS-G) subscale. However, there was a significant correlation between the degrees of hemispheric synchronization and the ability to keep still during 12-minute MEG recording periods. Our results also suggested that asynchrony in the bilateral brain auditory processing system is associated with ADHD-like symptoms in children with ASD.

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