Synthesis and Bleaching Activity of 1,5-Disubstituted Imidazoles

Naotaka Yamada, Eiichi Kuwano, Masamichi Kikuchi, Morifusa Eto

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

A variety of 1,5-disubstituted imidazoles and related compounds were prepared, and their bleaching activity was evaluated by using the lettuce seedling test. 5-(4-Benzyloxyphenyl)-l-ethylimidazole (13) caused clear chlorosis, while the 2- and 3-benzyloxyphenyl analogs had no activity. In the 5-(4-benzyloxyphenyl)imidazole series, only the 1-propyl analog showed significant activity, as well as compound 13. Both substituents at the 1- and 5-position of the imidazole ring were indispensable for this activity. Of the series of compounds tested, l-ethyl-5-stilbenylimidazole (22) and 5-[4-(3-chlorobenzyloxy)phenyl]-l-ethylimid-azole (33) showed the highest activity. Compound 33 at 30 ppm decreased the chlorophyll content in the lettuce seedlings to less than 20% of that in the control.

本文言語英語
ページ(範囲)1943-1948
ページ数6
ジャーナルBioscience, biotechnology, and biochemistry
56
12
DOI
出版ステータス出版済み - 1992

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 分析化学
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 分子生物学
  • 有機化学

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