Synthesis and relaxivities of oligonucleotides with TEMPO-labeled sugar moiety.

Manami Okazaki, Yuichiro Sato, Satoru Karasawa, Noboru Koga

研究成果: ジャーナルへの寄稿学術誌査読

1 被引用数 (Scopus)

抄録

5-Uridin derivative, UUT, having TEMPO radical at the 2'-position of sugar moiety, was prepared and characterized by X-ray crystallography. The single strands, ssUUT, incorporating UUT and the double strands, dsUUT, with complimentary strand were also obtained. Their EPR spectra and relaxivities (25 MHz and 0.59 T) in water were measured. The values of tau R obtained from the simulation of EPR spectra and the water-proton relaxivities, r1 and r2, increased in order of UUT, ssUUT, and dsUUT.

本文言語英語
ページ(範囲)375-376
ページ数2
ジャーナルNucleic acids symposium series (2004)
52
出版ステータス出版済み - 2008
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 医学(全般)

フィンガープリント

「Synthesis and relaxivities of oligonucleotides with TEMPO-labeled sugar moiety.」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル