Synthesis and self-assembly of C3-symmetric basic peptide conjugates

Aiko Kawaharada, Kazuya Murasato, Kazunori Matsuura, Nobuo Kimizuka

    研究成果: Chapter in Book/Report/Conference proceedingConference contribution

    抄録

    Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.

    本文言語英語
    ホスト出版物のタイトル54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
    ページ2050
    ページ数1
    54
    1
    出版ステータス出版済み - 2005
    イベント54th SPSJ Annual Meeting 2005 - Yokohama, 日本
    継続期間: 5 25 20055 27 2005

    その他

    その他54th SPSJ Annual Meeting 2005
    Country日本
    CityYokohama
    Period5/25/055/27/05

    All Science Journal Classification (ASJC) codes

    • Engineering(all)

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