Synthesis and structural characterization of nanoapatite ceramics powders for biomedical applications

Kanae Ando, Mizuki Ohkubo, Satoshi Hayakawa, Kanji Tsuru, Akiyoshi Osaka, Eiji Fujii, Koji Kawabata, Christian Bonhomme, Florence Babonneau

研究成果: Contribution to journalConference article査読

1 被引用数 (Scopus)


Zn/HAp particles were prepared by soaking hydroxyapatite (HAp), derived through a wet chemical method, into aqueous solutions containing various amounts of zinc nitrate. Obtained samples were characterized by inductively coupled plasma emission spectroscopy, X-ray diffraction (XRD), Brunauer-Emmett-Teller surface area analysis (SA), and transmission electron microscopy. Their zeta potential was also measured. The analyzed Zn content was almost proportional to the content in the aqueous solutions. The Zn 2+ ions were partially replaced the Ca 2+ ions in the apatite, and hence, little change was observed in crystallinity, particle size and SA. Adsorption of bovine serum albumin (BSA) and ß 2-microglobulin (ß 2-MG) in the solutions containing both BSA and ß 2-MG was examined. As the Zn 2+ ion content in the apatites increased, the adsorbed amount of BSA was almost constant, whereas that of ß 2-MG increased. Thus, the Zn incorporation increased the selectivity, and it is suggested that the Zn-substituted site should be the active ones for ß 2-MG adsorption.

ジャーナルCeramic Transactions
出版ステータス出版済み - 7 24 2006
イベント6th Pacific Rim Conference on Ceramic and Glass Technology, PacRim6 - Maui, HI, 米国
継続期間: 9 11 20059 16 2005

All Science Journal Classification (ASJC) codes

  • セラミックおよび複合材料
  • 材料化学


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