Synthesis of ω-fluorinated octanoic acid and its β-substituted derivatives

Fumi Nagatsugi, Shigeki Sasaki, Minoru Maeda

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

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Simple syntheses are described for the ω-fluorinated analogs of octanoic acid and its β-substituted derivatives in which insertion of a methyl and dimethyl group, and oxygen substitution at the C-3 position are involved, employing nucleophilic displacement with fluoride ion of the tosylate functions in the later stage of synthesis. The synthetic procedures offer easy and convenient access to the corresponding 18F-labeled analogs using the readily available [18F]fluoride ion.

元の言語英語
ページ(範囲)373-383
ページ数11
ジャーナルJournal of Fluorine Chemistry
56
発行部数3
DOI
出版物ステータス出版済み - 3 1992

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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