TY - JOUR
T1 - Synthesis of 20‐[18F]fluoroarachidonic acid
T2 - A potential phospholipid metabolic agent
AU - Nagatsugi, Fumi
AU - Hokazono, Junji
AU - Sasaki, Shigeki
AU - Maeda, Minoru
PY - 1994/1/1
Y1 - 1994/1/1
N2 - A fluorine‐18 labelled analog of arachidonic acid, 20‐[18F]fluoroarachidonic acid, was prepared for evaluation as a potential phospholipid metabolic agent. The radiosynthesis was accomplished by [18F]fluoride ion displacement on the tosylate precursor followed by basic hydrolysis of the ester group, in isolated radiochemical yield (not decay corrected) of 10 % in overall synthesis time (including HPLC purification) of 110 min.
AB - A fluorine‐18 labelled analog of arachidonic acid, 20‐[18F]fluoroarachidonic acid, was prepared for evaluation as a potential phospholipid metabolic agent. The radiosynthesis was accomplished by [18F]fluoride ion displacement on the tosylate precursor followed by basic hydrolysis of the ester group, in isolated radiochemical yield (not decay corrected) of 10 % in overall synthesis time (including HPLC purification) of 110 min.
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U2 - 10.1002/jlcr.2580341202
DO - 10.1002/jlcr.2580341202
M3 - Article
AN - SCOPUS:0027996514
SN - 0362-4803
VL - 34
SP - 1121
EP - 1127
JO - Journal of Labelled Compounds and Radiopharmaceuticals
JF - Journal of Labelled Compounds and Radiopharmaceuticals
IS - 12
ER -