Synthesis of endogenous sperm-activating and attracting factor isolated from ascidian Ciona intestinalis

Tohru Oishi, Hiroshi Tsuchikawa, Michio Murata, Manabu Yoshida, Masaaki Morisawa

研究成果: Contribution to journalArticle査読

22 被引用数 (Scopus)

抄録

A chemoattractant candidate named sperm-activating and attracting factor (SAAF) from the eggs of ascidian Ciona intestinalis, was synthesized from chenodeoxycholic acid in 16 steps. The present synthesis led to the unambiguous structure determination of SAAF to be (3R,4R,7R,25S)-3,4,7,26-tetrahydroxycholestane-3,26-disulfate. The synthetic pure specimen was also used to confirm the dual sperm-activating and attracting activity.

本文言語英語
ページ(範囲)6387-6389
ページ数3
ジャーナルTetrahedron Letters
44
34
DOI
出版ステータス出版済み - 8 18 2003
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生化学
  • 創薬
  • 有機化学

フィンガープリント

「Synthesis of endogenous sperm-activating and attracting factor isolated from ascidian Ciona intestinalis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル