抄録
We synthesized azo dye- and fluorescence-labeled cis-cinnamic acid analogues possessing inhibitory activity against lettuce root growth and a trans-isomer without bioactivity as a control probe. The radicles incubated with the azo dye-labeled analogue were stained red, with their tips especially deeply dyed. The fluorescent images of the radicles incubated with each of these molecular probes depicted that the root cap was fluorescence-stained. However, images of the control radicles prepared by staining with the trans-isomer fluorescent probe did not show emission at the root cap. These contrasts suggest specific localization of the cis-cinnamate analogue at the columella cells.
元の言語 | 英語 |
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ページ(範囲) | 6492-6498 |
ページ数 | 7 |
ジャーナル | Tetrahedron |
巻 | 72 |
発行部数 | 41 |
DOI | |
出版物ステータス | 出版済み - 1 1 2016 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
これを引用
Synthesis of fluorescent molecular probes based on cis-cinnamic acid and molecular imaging of lettuce roots. / Fukuda, Hiroshi; Nishikawa, Keisuke; Fukunaga, Yukihiro; Okuda, Katsuhiro; Kodama, Kozue; Matsumoto, Kenji; Kano, Arihiro; Shindo, Mitsuru.
:: Tetrahedron, 巻 72, 番号 41, 01.01.2016, p. 6492-6498.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Synthesis of fluorescent molecular probes based on cis-cinnamic acid and molecular imaging of lettuce roots
AU - Fukuda, Hiroshi
AU - Nishikawa, Keisuke
AU - Fukunaga, Yukihiro
AU - Okuda, Katsuhiro
AU - Kodama, Kozue
AU - Matsumoto, Kenji
AU - Kano, Arihiro
AU - Shindo, Mitsuru
PY - 2016/1/1
Y1 - 2016/1/1
N2 - We synthesized azo dye- and fluorescence-labeled cis-cinnamic acid analogues possessing inhibitory activity against lettuce root growth and a trans-isomer without bioactivity as a control probe. The radicles incubated with the azo dye-labeled analogue were stained red, with their tips especially deeply dyed. The fluorescent images of the radicles incubated with each of these molecular probes depicted that the root cap was fluorescence-stained. However, images of the control radicles prepared by staining with the trans-isomer fluorescent probe did not show emission at the root cap. These contrasts suggest specific localization of the cis-cinnamate analogue at the columella cells.
AB - We synthesized azo dye- and fluorescence-labeled cis-cinnamic acid analogues possessing inhibitory activity against lettuce root growth and a trans-isomer without bioactivity as a control probe. The radicles incubated with the azo dye-labeled analogue were stained red, with their tips especially deeply dyed. The fluorescent images of the radicles incubated with each of these molecular probes depicted that the root cap was fluorescence-stained. However, images of the control radicles prepared by staining with the trans-isomer fluorescent probe did not show emission at the root cap. These contrasts suggest specific localization of the cis-cinnamate analogue at the columella cells.
UR - http://www.scopus.com/inward/record.url?scp=84987947975&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84987947975&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2016.08.060
DO - 10.1016/j.tet.2016.08.060
M3 - Article
AN - SCOPUS:84987947975
VL - 72
SP - 6492
EP - 6498
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 41
ER -