@article{2eb24afc83b8467a91a4b7246421254c,
title = "Synthesis of fluorescent molecular probes based on cis-cinnamic acid and molecular imaging of lettuce roots",
abstract = "We synthesized azo dye- and fluorescence-labeled cis-cinnamic acid analogues possessing inhibitory activity against lettuce root growth and a trans-isomer without bioactivity as a control probe. The radicles incubated with the azo dye-labeled analogue were stained red, with their tips especially deeply dyed. The fluorescent images of the radicles incubated with each of these molecular probes depicted that the root cap was fluorescence-stained. However, images of the control radicles prepared by staining with the trans-isomer fluorescent probe did not show emission at the root cap. These contrasts suggest specific localization of the cis-cinnamate analogue at the columella cells.",
author = "Hiroshi Fukuda and Keisuke Nishikawa and Yukihiro Fukunaga and Katsuhiro Okuda and Kozue Kodama and Kenji Matsumoto and Arihiro Kano and Mitsuru Shindo",
note = "Funding Information: We thank Prof. Y. Fujii, Dr. N. Wasano (Tokyo University of Agriculture and Technology) and Prof. M. Morita (Nagoya University) for helpful discussions. This work was supported by the Program for Promotion of Basic and Applied Research for Innovations in the Bio-oriented Industry (BRAIN) from the Bio-oriented Technology Research Advancement Institution , Science and Technology Research Promotion Program for Agriculture, Forestry, Fisheries and Food Industry (No. 25029AB), Japan Society for the Promotion of Science (JSPS) KAKENHI Grant numbers JP26293004 , JP2667003 , JP16H01157 (M.S.), and JP23790131 (K.M.). ",
year = "2016",
doi = "10.1016/j.tet.2016.08.060",
language = "English",
volume = "72",
pages = "6492--6498",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "41",
}