Synthesis of gene carrier responding with tyrosine kinase 'c-Src' and functional control

Keiko Terada, Yuko Sato, Jun Ohishi, Kenji Kawamura, Jeong Hun Kang, Daisuke Asai, Yoshiki Katayama

    研究成果: Contribution to conferencePaper査読

    抄録

    We designed a gene carrier that can activate the delivered gene in response to the intercellular kinase signal. 'c-Src', which is non-receptor tyrosine kinase, is specifically activated within a cancer cell. We create gene carrier to express a therapeutics gene in response to 'c-Src'. We synthesize polymers that are grafted c-Src substrate peptide as an intercellular signal-response gene carrier. We will discuss the design of c-Src responsive carriers and their abilities for target signal specific gene regulation.

    本文言語英語
    ページ数1
    出版ステータス出版済み - 10 19 2006
    イベント55th SPSJ Annual Meeting - Nagoya, 日本
    継続期間: 5 24 20065 26 2006

    その他

    その他55th SPSJ Annual Meeting
    国/地域日本
    CityNagoya
    Period5/24/065/26/06

    All Science Journal Classification (ASJC) codes

    • 工学(全般)

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