TY - JOUR
T1 - Synthesis of phosphorofluoridate analogues of myo-inositol 1,4,5-tris(phosphate) and their biological activity
AU - Watanabe, Yutaka
AU - Sofue, Shinsuke
AU - Ozaki, Shoichiro
AU - Hirata, Masato
PY - 1996/1/1
Y1 - 1996/1/1
N2 - Phosphorofluoridate analogues of myo-inositol 1,4,5-tris(phosphate), 4- and 5-phosphorofluoridate and 4,5-bis(phosphorofluoridate), were prepared and their biological activity towards InsP3 5-phosphatase was found to be similar to or more active than that for InsP3 while they proved to be less active in the binding assay than InsP3.
AB - Phosphorofluoridate analogues of myo-inositol 1,4,5-tris(phosphate), 4- and 5-phosphorofluoridate and 4,5-bis(phosphorofluoridate), were prepared and their biological activity towards InsP3 5-phosphatase was found to be similar to or more active than that for InsP3 while they proved to be less active in the binding assay than InsP3.
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U2 - 10.1039/cc9960001815
DO - 10.1039/cc9960001815
M3 - Article
AN - SCOPUS:1842473205
SP - 1815
EP - 1816
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 15
ER -