Synthesis of the 1β-Methylcarbapenem Key Intermediates

Yoshio Ito, Shiro Terashima

研究成果: Contribution to journalArticle査読

24 被引用数 (Scopus)

抄録

The 1β-methylcarbapenem antibiotics represented by 3, 4, and 5, have been the focus of current synthetic endeavor due to prominent antibacterial activities and broad spectra as well as enhanced chemical and metabolic stability. Progress of the syntheses of 1β-methylcarbapenem key intermediates represented by 6, are reviewed based on the synthetic methods of the characteristic 1β-methyl substituent involved in the contiguous four chiral centers of 6.

本文言語英語
ページ(範囲)606-618
ページ数13
ジャーナルJournal of Synthetic Organic Chemistry, Japan
47
7
DOI
出版ステータス出版済み - 1989
外部発表はい

All Science Journal Classification (ASJC) codes

  • 有機化学

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