Telomerase and oral cancer

T. Sumida, H. Hamakawa

研究成果: Contribution to journalShort survey査読

12 被引用数 (Scopus)

抄録

The development of malignant neoplasms is a multistep process and it is believed that multiple genetic alterations are involved. The progression of neoplastic lesions is also characterized by reactivation of telomerase, a ribonucleoprotein complex enzyme that adds telomere repeats at the ends of chromosomes. In view of the close association between telomerase and malignancy, this molecule may prove to be a useful marker for malignancy. This review focuses on the diagnostic and therapeutic potential of telomerase. The experimental data for telomerase assays with the potential for oral cancer detection and diagnosis are also reviewed.

本文言語英語
ページ(範囲)333-340
ページ数8
ジャーナルOral Oncology
37
4
DOI
出版ステータス出版済み - 1 1 2001

All Science Journal Classification (ASJC) codes

  • 口腔外科
  • 腫瘍学
  • 癌研究

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