Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate

Masaharu Murata, Wataru Kaku, Takahisa Anada, Yoshikuni Sato, Mizuo Maeda, Yoshiki Katayama

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抄録

We prepared a novel antisense reagent comprising of oligodeoxynucleotides (ODNs) and a thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate demonstrated stimuli-responsive regulation of gene expression via conformational change of the polymer chain.

元の言語英語
ページ(範囲)986-987
ページ数2
ジャーナルChemistry Letters
32
発行部数11
DOI
出版物ステータス出版済み - 11 5 2003

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Polymers
Oligodeoxyribonucleotides
DNA
Gene expression
Temperature
poly-N-isopropylacrylamide

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

これを引用

Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate. / Murata, Masaharu; Kaku, Wataru; Anada, Takahisa; Sato, Yoshikuni; Maeda, Mizuo; Katayama, Yoshiki.

:: Chemistry Letters, 巻 32, 番号 11, 05.11.2003, p. 986-987.

研究成果: ジャーナルへの寄稿記事

Murata, Masaharu ; Kaku, Wataru ; Anada, Takahisa ; Sato, Yoshikuni ; Maeda, Mizuo ; Katayama, Yoshiki. / Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate. :: Chemistry Letters. 2003 ; 巻 32, 番号 11. pp. 986-987.
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