Testosterone/dihydrotestosterone

Yukiko Ogino, Shinichi Miyagawa, Taisen Iguchi

研究成果: 書籍/レポート タイプへの寄稿

抄録

Androgens are critical steroid hormones that regulate male sexual development and differentiation, including the formation of the reproductive system and the maintenance of its function. Androgens are also essential in muscle development and psychosexual behavior. Testosterone and dihydrotestosterone act as the predominant androgens in mammals. Androgens mediate their effects through the androgen receptor (AR), a member of the nuclear receptor superfamily. Liganded AR is translocated from the cytoplasm to the nucleus and regulates the transcription of androgen-responsive genes. Mutations in the AR result in diseases such as androgen insensitivity syndrome, prostate cancer, Kennedy’s disease, and infertility.

本文言語英語
ホスト出版物のタイトルHandbook of Hormones
ホスト出版物のサブタイトルComparative Endocrinology for Basic and Clinical Research
出版社Elsevier
ページ917-920
ページ数4
ISBN(電子版)9780128206492
DOI
出版ステータス出版済み - 1月 1 2021

!!!All Science Journal Classification (ASJC) codes

  • 医学(全般)

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