Tetrodotoxin- and tributyltin-binding abilities of recombinant pufferfish saxitoxin and tetrodotoxin binding proteins of Takifugu rubripes

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

We investigated the ability of recombinant pufferfish saxitoxin and tetrodotoxin binding protein types 1 and 2 of Takifugu rubripes (rTrub.PSTBP1 and rTrub.PSTBP2) to bind to tetrodotoxin (TTX) and tributyltin. Both rTrub.PSTBPs bound to tributyltin in an ultrafiltration binding assay but lost this ability on heat denaturation. In contrast, only rTrub.PSTBP2 bound to TTX even heat denaturation. This result suggests that the amino acid sequence of PSTBP2 may be contributed for its affinity for TTX.

本文言語英語
ページ(範囲)50-52
ページ数3
ジャーナルToxicon
125
DOI
出版ステータス出版済み - 1 1 2017

All Science Journal Classification (ASJC) codes

  • 毒物学

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「Tetrodotoxin- and tributyltin-binding abilities of recombinant pufferfish saxitoxin and tetrodotoxin binding proteins of Takifugu rubripes」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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