The action of the cholecystokinin-A receptor antagonist, devazepide, on the digestive system of the chicken

M. Furuse, Y. H. Choi, S. Satoh, J. Okumura

研究成果: ジャーナルへの寄稿記事

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The influence of the cholecystokinin (CCK)-A receptor antagonist, devazepide (DVZ), on the chicken digestive tract was investigated. The passage of food from the crops of birds treated with DVZ was not significantly different from that of the control. DVZ treatment did not inhibit the biliary flow stimulated by the CCK analogue, caerulein. Dispersed chicken pancreatic acini stimulated with CCK were treated with various concentrations of DVZ. At 10-5 M, DVZ completely inhibited amylase release; this concentration was much higher than those reported to have similar effects in mammals. The results suggest that the action DVZ as a CCK antagonist in the chicken is very weak.

元の言語英語
ページ(範囲)353-356
ページ数4
ジャーナルExperientia
52
発行部数4
DOI
出版物ステータス出版済み - 4 1 1996
外部発表Yes

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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