The cooling performance of a cryoprobe: Establishing guidelines for the safety margins in cryosurgery

Mohammed Shurrab, Haidong Wang, Noriaki Kubo, Takanobu Fukunaga, Kosaku Kurata, Hiroshi Takamatsu

研究成果: ジャーナルへの寄稿学術誌査読

19 被引用数 (Scopus)

抄録

Cryosurgery is a minimally invasive surgical technique that uses cryoprobes or cryoneedles to freeze and destroy tumors or undesirable tissues. It is supported by non-invasive monitoring technologies such as MRI and ultrasonography, which make it possible to distinguish frozen regions in tissues and organs. However, the application of an ice ball to a cancerous tissue cannot guarantee the eradication of the complete tumor. Exposing all cancer cells to the lethal temperature, while minimizing the exposure of the healthy tissue to avoid side effects, is necessary. Therefore, the size of the ice ball is a key issue in cryosurgery. However, no data on the performance of clinically used cryoprobes are available in the open literature. The objective of this study was to experimentally validate the cooling performance of a widely used Joule-Thomson cryoprobe, to investigate the growth of the ice ball and cooling power of the probe, and to suggest guidelines for establishing the safety margin at the ice periphery. A numerical simulation was also carried out, and the results were compared with the experimental findings.

本文言語英語
ページ(範囲)308-318
ページ数11
ジャーナルInternational Journal of Refrigeration
67
DOI
出版ステータス出版済み - 7月 1 2016

!!!All Science Journal Classification (ASJC) codes

  • 建築および建設
  • 機械工学

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